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目的：探讨多系统萎缩（ＭＳＡ）的影像学特征与临床表现的相关性，为临床诊断提供依据。方法：对２３例临床资料进行回顾性分析。结果：根据临床资料及影像结果分为３类型。（１）１６例橄榄体桥小脑萎缩（ＯＰＣＡ）中，以小脑共济失调为主者１０例，脑的ＣＴ或ＭＲＩ可见桥脑、橄榄体、小脑萎缩明显，可伴大脑等部位萎缩；（２）３例Ｓｈｙ－Ｄｒａｇｅｒ综合征（ＳＤＳ），以植物神经功能紊乱为主要表现者２例，１例误诊为多发脑梗塞，脑ＭＲＩ壳核Ｔ２低信号改变；（３）４例纹状体－黑质变性（ＳＮＤ）首发症状均为锥体外系表现而误诊为帕金森病。脑ＭＲＩ示壳核可有Ｔ１低Ｔ２高信号改变。结论：ＭＳＡ是一组神经系统多部位变性综合征，各型早期各具特点，其中ＳＤＳ、ＳＮＤ较易误诊；ＭＲＩ等有关检测技术对发病机理和诊断分型等方面有较肯定的意义
Objective: To investigate the correlation between the imaging features of multiple system atrophy (MSA) and clinical manifestations and provide the basis for clinical diagnosis. Methods: The clinical data of 23 cases were retrospectively analyzed. Results: According to the clinical data and imaging results are divided into 3 types. (1) Of the 16 patients with olivopontocerebellar atrophy (OPCA), 10 cases were mainly cerebral ataxia. The pons and olivosus and cerebellar atrophy of the brain could be seen by CT or MRI of brain. 2) 3 cases of Shy-Drager syndrome (SDS), autonomic dysfunction as the main performance in 2 cases, 1 case misdiagnosed as multiple cerebral infarction, brain MRI nuclear hypoplasia T2 low signal change; (3) 4 cases of striatum - The first symptoms of substantia nigra degeneration (SND) are extrapyramidal manifestations and misdiagnosed as Parkinson’s disease. Brain MRI showed that the shell core may have T1 low T2 high signal changes. Conclusion: MSA is a group of multiple degeneration syndromes of the nervous system. Each type has its own characteristics in the early stage, of which SDS and SND are easy to be misdiagnosed. MRI and other related detection techniques have more positive significance on the pathogenesis and diagnostic typing