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目的 探讨术中放射治疗 (简称放疗 )对晚期胰腺癌的疗效。方法 使用直线加速器 ,对 1986～ 1997年期间收住我院 ,伴有严重背痛和腹痛的无法切除的晚期胰腺癌患者 45例进行术中放疗。结果 本组患者背痛和腹痛的完全缓解率为 5 6 % ,部分缓解率为 40 %。平均生存期为7 5个月。同期进行的 30例胰腺癌切除患者 ,其平均生存期为 7个月 ,两者差异无显著意义。结论 术中放疗尽管不能明显延长晚期胰腺癌患者的平均生存期 ,但能明显缓解患者的疼痛 ,提高患者的生活质量 ,仍然不失为一种有效的晚期胰腺癌姑息治疗方法。
Objective To investigate the effect of intraoperative radiotherapy (referred to as radiotherapy) on advanced pancreatic cancer. Methods Using a linear accelerator, 45 patients with unresectable advanced pancreatic cancer admitted to our hospital from 1986 to 1997 with severe back pain and abdominal pain were treated with intraoperative radiotherapy. Results The complete remission rate of pain and abdominal pain in this group was 56% and the partial remission rate was 40%. The average survival time was 75 months. In the same period, 30 patients with pancreatic cancer resected had an average survival of 7 months, with no significant difference between the two groups. Conclusion Although intraoperative radiotherapy can not significantly prolong the average survival of patients with advanced pancreatic cancer, but can significantly relieve pain and improve patient quality of life, is still an effective palliative treatment of advanced pancreatic cancer.