随着降血脂药物的开发,过去难于治疗的。以家族性高脂血症为代表的难治性高脂血症也有可能得到有效的治疗。日本大学第二内科的水野学氏,应用具有抑制肝脏合成胆固醇并能促进其排泄的药物丙丁酚(Probucol)与在肠管内能减少胆固醇吸收的消胆胺(Cholestyramiue)并用,使难治性高脂血症疗效大大提高。 With the development of hypolipidemic drugs, the past is difficult to treat. Refractory hyperlipidemia, represented by familial hyperlipidemia, may also be treated effectively. The second internal medicine of Nihon University School of Medicine, the use of a compound that inhibits the synthesis of cholesterol in the liver can promote its excretion of Probucol and cholesterol in the intestine to reduce cholesterol absorption of cholestyramine (Cholestyramiue) and use, so refractory high The efficacy of lipids greatly increased.