牛扁别名曲芍,系毛茛科乌头属植物(Aconitum barbatum Pers var. puberulum Ledeb.),主要分布在我国北部地区。民间用其根治疗慢性支气管炎、关节肿痛及淋巴结核等病。该植物化学成分的研究尚未见报道。作者采用干柱层析结合制备薄层的方法,从其总生物碱中分得9种生物碱,其中5种经鉴定为已知生物碱ranaconitine(1),拉杷乌头碱(lappaconitine, Niuqian is also known as Qufu (Aconitum barbatum Pers var. puberulum Ledeb.), which is mainly distributed in northern China. The folk use their roots to treat diseases such as chronic bronchitis, joint swelling, and lymphatic tuberculosis. The study of the chemical composition of the plant has not been reported. The authors used dry-column chromatography in combination with thin layers to prepare nine alkaloids from their total alkaloids, five of which were identified as the known alkaloids ranaconitine (1) and laptopitine (