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低分子肝素(LMWH)是由肝素经降解得到的低分子量的肝素片段或经分级法得到的低分子量组分,与标准肝素相比具有抗血栓作用强、出血副作用小、生物利用度高、半衰期长等特点。目前LMWH均为注射剂,作为防治血栓的药物具有长期用药不方便的缺点。为此,我们研制了其透皮吸收制?
Low Molecular Weight Heparin (LMWH) is a low molecular weight heparin fragment obtained by degradation of heparin or a fractionated low molecular weight component that has antithrombotic effects, small bleeding side effects, high bioavailability, half-life compared with standard heparin Long and so on. Currently LMWH are injection, as the prevention and treatment of thrombosis drugs with the shortcomings of inconvenient long-term medication. To this end, we developed its system of transdermal absorption?