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重症肌无力(myasthenia gravis,MG)是一种神经肌肉接头传递障碍疾病,以骨骼肌无力、晨轻暮重、症状有波动为主要临床特点。近年来老年MG的发病率逐年增加,新发现的一些抗体(anti-MusK和anti-LRP4)能诊断原抗体检测难以诊断的MG,新的电生理诊断方法(单纤维肌电图和双神经刺激试验)能发现常规肌电图不能发现的神经肌肉接头处突触传递障碍,新涌现的治疗药物(单抗隆抗体和粒白细胞集
Myasthenia gravis (MG) is a disorder of neuromuscular junction delivery disorder, with skeletal muscle weakness, morning and evening heavy, the symptoms of fluctuations as the main clinical features. In recent years, the incidence of geriatric MG has been increasing year by year. Some newly discovered antibodies (anti-MusK and anti-LRP4) can diagnose MG which is difficult to diagnose using the original antibody. The new electrophysiological diagnostic methods (single fiber electromyography and double nerve stimulation Test) can find synaptic delivery disorders at neuromuscular junctions that can not be found with conventional electromyography, emerging therapeutic drugs (mAbs and leukocytes