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过去对静脉注射氨茶碱对脑血管的作用究竟是扩张还是收缩,以及治疗急性脑血管疾病有无疗效意见都不一致。1970年Skinhoi及Paulson对急性脑梗塞病人进行局部脑血流量测定表明氨茶碱的作用是一种“倒的脑内盗血现象”,即脑的正常部位血管收缩,使血液转流到局部缺血的区域。如氨茶碱治疗脑血管疾病有效,则有使用方便价格便宜的优点。为了正确的评价氨茶碱对急性脑梗塞病人的疗效,作者对79例急性脑梗塞住院病人进行了双盲法对照
In the past on the role of intravenous aminophylline on cerebrovascular expansion or contraction, as well as the treatment of acute cerebrovascular disease whether the efficacy of the views are inconsistent. Skinhoi and Paulson’s assessment of regional cerebral blood flow in patients with acute cerebral infarction in 1970 showed that the effect of aminophylline was an “inverted intracerebral steal phenomenon”, the vasoconstriction of the normal part of the brain, causing blood to flow to a localized absence Blood area. Such as aminophylline treatment of cerebrovascular disease is effective, there are advantages of easy to use cheap. In order to correctly evaluate the efficacy of aminophylline in patients with acute cerebral infarction, the authors conducted a double-blind control study of 79 patients with acute cerebral infarction