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目的:研究分析空肠内营养与全胃肠外营养对重症急性胰腺炎患者的疗效及免疫功能影响。方法:随机选取我院2011年12月至2013年6月治疗的74例急性重症胰腺炎患者,对所有患者采取随机分组的方法分为空肠内营养组和全胃肠外营养组,每组患者各37例。对比两组患者的疗效和血清IgG、IgA、IgM的水平,以及感染等并发症的情况等。结果:两组的临床疗效为空肠内营养组显效18例、有效11例、无效8例,全胃肠外营养组显效17例、有效13、无效7例,对比两组临床疗效,差异无统计学意义且P>0.05。空肠内营养组发生感染患者8例(21.62%),而全胃肠外营养组15例(40.54%),对比两组患者感染率,差异有统计学意义且P<0.05。治疗一周后,对比两组患者的血清水平,空肠内营养组均高于全胃肠外营养组。结论:空肠内营养组和全胃肠外营养组对于治疗急性重症胰腺炎的效果相似,无明显差异,但空肠内营养组相对来说可以有效降低患者的感染风险,使患者抵抗力提高,因此,应及早实施空肠内营养。
Objective: To study the effects of jejunal nutrition and total parenteral nutrition on patients with severe acute pancreatitis and its immune function. Methods: Seventy-four patients with acute severe pancreatitis treated in our hospital from December 2011 to June 2013 were selected randomly. All patients were randomly divided into jejunal nutrition group and total parenteral nutrition group. Patients in each group 37 cases each. Compare the curative effect of two groups of patients and serum IgG, IgA, IgM levels, and complications such as infection. Results: The clinical efficacy of the two groups was markedly effective in jejunal nutrition group 18 cases, effective in 11 cases, ineffective in 8 cases, total parenteral nutrition group markedly effective in 17 cases, effective 13, ineffective in 7 cases, compared the two groups of clinical efficacy, the difference was not statistically Significance and P> 0.05. There were 8 cases (21.62%) in the jejunal nutrition group and 15 cases (40.54%) in the total parenteral nutrition group. The difference was statistically significant (P <0.05). After a week of treatment, the serum levels of both groups were compared, and the jejunal nutrition group was higher than the total parenteral nutrition group. CONCLUSION: The jejunal nutrition group and total parenteral nutrition group have similar effects on the treatment of acute severe pancreatitis, but there is no significant difference between them. However, the jejunal nutrition group can reduce the patients ’infection risk relatively and increase the patients’ resistance. Therefore, , Should be implemented as early as jejunal nutrition.