口腔粘膜黑色素沉着,特别是由银尖根充所致的色素沉着与黑色素瘤的诊断需十分慎重。由于对疑为黑色素瘤的病损,禁忌在术前进行活检,为此较难确诊。我们曾遇到几例因银尖根充所致的口腔粘膜黑色素沉着,现就其中一例报告如下。病例:患者,男,37岁,因牙痛就诊。发现上颌左第4牙轻度松动,颌面汞 The melanin pigmentation of the oral mucosa, especially the hyperpigmentation caused by the silver tip root filling and the diagnosis of melanoma must be very careful. Because of the lesions of suspected melanoma, it is contraindicated that preoperative biopsy is difficult to diagnose. We have encountered several cases of melanin pigmentation of the oral mucosa caused by silver tip root filling. One case report is as follows. Case: Patient, male, 37 years old, treated for toothache. Found that the left maxillary 4th tooth is slightly loose, maxillofacial mercury