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[目的]观察中西医结合治疗耐多药肺结核(MDR-TB)疗效。[方法]观察50例,随机分为治疗组25例,对照组25例。两组均采用西药抗痨药物治疗,治疗组在常规治疗方法的基础上加用中药,疗程3个月,观察两组的疗效差异。[结果]治疗1、3、6月末,治疗组的痰菌阴转率分别为60%、92%、96%,高于对照组48%、60%、92%,两组疗效对比有显著性差异(P=0.018)。同时观察两组治疗3月后胸片吸收情况,治疗组明显改善12例,中度改善9例,轻度改善2例,无改善2例;对照组明显改善8例,中度改善4例,轻度改善5例,无改善7例,统计学显示两者有显著差异(P=0.032)。[结论]中西医结合治疗耐多药肺结核疗效优于单纯用西药治疗。
[Objective] To observe the curative effect of traditional Chinese medicine and western medicine on multidrug-resistant pulmonary tuberculosis (MDR-TB). [Method] Fifty cases were observed and randomly divided into treatment group (25 cases) and control group (25 cases). The two groups were treated with western medicine anti-tuberculosis drugs. The treatment group was given traditional Chinese medicine on the basis of conventional treatment. The course of treatment was 3 months. The difference in curative effect between the two groups was observed. [Results] The sputum negative conversion rates of the treatment group were 60%, 92% and 96% respectively at the end of 1, 3 and 6 months, which were significantly higher than those of the control group (48%, 60% and 92% Difference (P = 0.018). At the same time, we observed the absorption of chest radiograph in the two groups after treatment for 3 months. The treatment group improved significantly in 12 cases, moderate improvement in 9 cases, mild improvement in 2 cases, no improvement in 2 cases. The control group improved significantly in 8 cases, moderate improvement in 4 cases, Slight improvement in 5 cases, no improvement in 7 cases, the statistics showed a significant difference between the two (P = 0.032). [Conclusion] Integrative treatment of MDR-TB is superior to western medicine alone.