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指南推荐血压目标值应<140/90 mm Hg(1mm Hg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。因此,对于不同的终点事件,高基线收缩压与低目标收缩压相关的风
Guidelines recommend that blood pressure target values should be <140/90 mm Hg (1 mm Hg = 0.133 kPa) to reduce cardiovascular events. However, the prognosis of cardiovascular disease, including stroke and heart failure, is more closely related to the reduction of systolic blood pressure than other cardiovascular outcomes (such as coronary events). The risk of some cardiovascular events (such as coronary events) also increases when systolic blood pressure is low, and the risk-systolic blood pressure is J-shaped, whereas stroke and blood pressure are not J-shaped. Therefore, for different endpoints, high baseline systolic blood pressure associated with low target systolic pressure