本文报道了六种新的嘧啶衍生物:N,N′-二(ω-羟乙基)-5-氟尿嘧啶-1,3-双乙酰胺,N,N′-二(ω-羟丙基)-5-氟尿嘧啶-1,3-双乙酰胺,N,N′-二(ω-羟乙基)尿嘧啶-1,3-双乙酰胺,N,N′-二(ω-羟丙基)尿嘧啶-1,3-双乙酰胺,N,N′-二(ω-羟乙基)胸腺嘧啶-1,3-双乙酰胺,N,N′-二(ω-羟丙基)胸腺嘧啶-1,3-双乙酰胺的合成。通过元素分析,~1H核磁共振潜,红外光谱和紫外光谱测定了化合物的结构。这些化合物可作为单体用于高分子抗癌药物的合成。 Six novel pyrimidine derivatives were reported: N, N’-bis (ω-hydroxyethyl) -5-fluorouracil- (Ω-hydroxyethyl) uracil-1,3-diacetamide, N, N’-bis (ω-hydroxypropyl) Uracil-1,3-bisacetamide, N, N’-bis (ω-hydroxyethyl) thymine-1,3-bisacetamide, N, N’-bis (ω-hydroxypropyl) thymine -1,3-diacetamide. The structures of the compounds were determined by elemental analysis, ~ 1H NMR, IR and UV spectra. These compounds can be used as monomers for the synthesis of high-molecular anticancer drugs.