生长、繁殖在胃上皮及十二指肠胃化生上皮表面粘液层内的幽门螺杆菌(Helicobacter pylori,HP)能引起胃炎,并与消化性溃疡的发生、发展及复发有密切联系,非溃疡性消化不良病人某些症状与 HP感染有关并可通过根除 HP 而得到缓解。HP 感染亦被认为是胃癌发生的高危因素之一。因此,根除HP 在胃肠疾病中具有重要意义。所谓 HP 的根除是指抗菌药物治疗疗程停止至少四周后检测 HP 转为阴性。治疗停止时 HP 转阴则称为清除(Clearance)。在治疗期间,HP 可仅发生数量 Helicobacter pylori (HP), which grows and propagates in the gastric mucosa of gastric epithelium and duodenum, can induce gastritis and is closely related to the occurrence, development and recurrence of peptic ulcer Some of the symptoms of dyspeptic patients are related to HP infection and can be alleviated by eradication of HP. HP infection is also considered one of the risk factors for gastric cancer. Therefore, eradicating HP is of great importance in gastrointestinal diseases. The so-called HP eradication refers to the anti-bacterial drug treatment stopped at least four weeks after the test HP turned negative. HP treatment is stopped when the negative is called Clearance (Clearance). HP can only occur during treatment