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目的 探讨老年慢性特发性便秘 (CIC)患者结肠运动功能变化及其与心理因素的关系。 方法 应用不透X线标记物法及Zung抑郁自评量表 (SDS)及焦虑自评量表 (SAS)对 5 9例老年CIC患者及 36例老年对照者进行结肠通过时间检查及心理状况分析。 结果 (1)老年CIC组全结肠及分段结肠通过时间较老年对照组明显延长 (P <0 0 5 ) ;(2 )长期服用泻药组的老年CIC患者其全结肠及分段结肠通过时间较间断服药和不服药者明显延长 (P <0 0 5 ) ;(3)老年CIC患者SDS、SAS标准总分均明显高于老年对照组 (P <0 0 5 ) ;(4 )老年CIC患者中结肠通过时间延长组SDS标准总分明显高于结肠通过时间正常组 (P <0 0 5 ) ,结肠通过时间正常组SAS标准总分明显高于结肠通过时间延长组 (P <0 0 5 )。 结论 老年CIC患者存在结肠动力学异常。抑郁情绪和焦虑情绪与老年CIC患者结肠运动功能异常有关。
Objective To investigate the changes of colonic motor function in elderly patients with chronic idiopathic constipation (CIC) and its relationship with psychological factors. Methods Fifty-nine elderly CIC patients and 36 elderly controls were enrolled in the study of colonic transit time and psychological status using radiopaque marker and Zung Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale (SAS) . Results (1) The passage time of the colon and segmental colon in the elderly CIC group was significantly longer than that in the elderly control group (P <0.05). (2) The long-term laxative group (P <0.05); (3) The scores of SDS and SAS in elderly patients with CIC were significantly higher than those in the elderly control group (P <0.05); (4) Among elderly CIC patients The score of SDS in colonic transit group was significantly higher than that in normal colonic transit group (P <0.05). The score of SAS in normal colonic passage group was significantly higher than that in colonic transit group (P <0.05). Conclusion The elderly patients with CIC have abnormal colonic motility. Depression and anxiety are associated with abnormal colonic motor function in elderly patients with CIC.