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目的 :无法手术根治或手术后多处转移的晚期大肠癌目前尚无理想有效的治疗方法 ,本文探讨用中西医结合的方法提高其治疗效果。方法 :对该院 5年多来收治的 85例无法手术根治或术后多处转移的晚期大肠癌患者进行前瞻性、可比性对照临床研究 ,考核其生存时间、生活质量、客观疗效指标、免疫指标和血流变指标。结果 :静脉联合化疗加中药“消疒徵 方”治疗组 (中西医组 )的生存率、生活质量明显优于单用化疗组 (χ2 检验 ,P <0 0 5 ) ;生存时间也较长 ,客观疗效指标二组间尚未显示出统计学差异 ;免疫指标 (CD3、CD4、CD8和NK)和血流变指标 ,中西医组的改善情况显著好于单纯化疗组 (t检验P <0 0 5 )。结论 :静脉联合化疗加中药“消疒徵 方”不失为一种较好的中西医结合治疗方法 ,副作用轻 ,总体治疗效果优于单纯化疗组 ,尤其是提高了晚期大肠癌患者的生活质量
Objective : There is no ideal and effective treatment for advanced colorectal cancer that cannot be radically treated or metastasized after surgery. This article discusses the use of integrated traditional Chinese and Western medicine to improve its therapeutic effect. METHODS: A prospective, comparable clinical study was performed on 85 patients with advanced colorectal cancer who had no surgery or multiple metastases after treatment in the hospital for more than five years. Their survival time, quality of life, objective efficacy indicators, and immunity were assessed. Indicators and blood rheological indicators. RESULTS: The survival rate and quality of life of intravenous chemotherapy combined with Chinese medicine “Xiefei Zhengfang” treatment group (Zhongxi Yipian) were significantly better than that of chemotherapy alone group (χ2 test, P <0 05); survival time was also longer. There were no statistically significant differences between the two groups in terms of objective efficacy indicators; immune parameters (CD3, CD4, CD8, and NK) and hemorrheology were significantly better in the Chinese and Western medicine groups than in the chemotherapy alone group (t test P<0 0 5 ). Conclusion: Combination of intravenous chemotherapy and traditional Chinese medicine “elimination of syndromes” is a good combination of Chinese and Western medicine treatment, side effects are light, the overall effect of treatment is better than chemotherapy alone, especially to improve the quality of life of patients with advanced colorectal cancer