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目的:通过观察内外结合攻补兼施法治疗小儿消化功能紊乱症脾虚夹积证的临床疗效,进一步探讨该法在临床治疗中的指导意义。方法:通过随机、平行、对照试验,将60例中医辨证为脾虚夹积型小儿消化功能紊乱症患儿,按比例1∶1,随机分为治疗组和对照组。治疗组予健脾消积颗粒剂内外结合治疗;对照组予健胃消食口服液内服治疗。结果:治疗组综合疗效明显优于对照组(P<0.05);治疗后主、次症总积分均有减少,治疗组主、次症总积分减少明显优于对照组(P<0.05);治疗组在改善饮食、面色、腹胀主症方面明显优于对照组(P<0.05);治疗组在改善精神、腹满、大便、舌象次症方面明显优于对照组(P<0.05)。结论:采用内外结合法,在攻补兼施理论指导下,运用健脾消积颗粒剂治疗小儿消化功能紊乱症脾虚夹积证疗效确切显著,值得全面推广。
Objective: To observe the clinical curative effect of combined treatment of both internal and external therapy in the treatment of digestive disorders in children with spleen deficiency syndrome, and to further explore the clinical significance of this method in clinical treatment. Methods: A randomized, parallel and controlled trial, 60 cases of syndrome differentiation of children with digestive disorders of the spleen type of infantile deficiency syndrome were randomly divided into treatment group and control group according to a ratio of 1: 1. The treatment group was treated with Jianpi Xiaoshi Granules both in vitro and in vivo; the control group was treated with Jianweixiaoshi oral solution orally. Results: The comprehensive efficacy of the treatment group was significantly better than that of the control group (P <0.05). After treatment, the total score of the primary and secondary symptoms decreased. The total score of the primary and secondary symptoms in the treatment group decreased significantly compared with the control group (P <0.05) The group was better than the control group in improving the main symptoms of diet, complexion and bloating (P <0.05). The treatment group was significantly better than the control group in improving the spirit, abdominal fullness, stool and tongue secondary symptoms (P <0.05). Conclusion: The combination of internal and external law, in the principle of both supplementation and therapy, the use of Jianpi Xiaoji granules for the treatment of digestive disorders in children with splenic syndrome is indeed significant and worthy of the full promotion.