1983年12月6日在昆明市召开了獐牙菜苦甙新药鉴定会,会议由云南省卫生厅、云南省医药总公司和云南省科委主持。獐牙菜苦甙是从斜茎獐牙菜Swertia patens Burk中提取得到的一种解痉止痛新药,从1981至1983年,云南省药物研究所对獐牙菜苦甙的提取、分离、结构鉴定、药理、毒理、中试工艺、药品质量标准等方面进行了研究,江西医学院协作进行了~3H—獐牙菜苦甙的药代动力学研究,云南省药品检验所协作进行厂药品质量标准的研究,楚雄州药品检验所协作进行了部分化学研究工作,由昆明市儿童医院、昆明医学院第一附属医院等9个临床协作医院完成了496例临床疗效观察。与会代表一致通过了技术鉴定,并认为獐牙菜苦甙有较好的平滑肌解痉作用和一定的镇痛、镇静作用。经496例临床观察,疗效满意。在496例中胃肠痉挛82例,有效80例,无效2例,有效率为97.5%;肠蛔虫症疼痛128例,有效119例,无效9例,有效率93%;胃肠炎疼痛128例,有效112例,无效16例,有效率为87.5%;胆道蛔虫症及其它胆道疾病疼痛64例,有效51例,无效13例,有效率为79.7%;其它疾患引起的腹痛94例,有效76例,无效18例,有效率为80.8%。在496个病例中,取得如下的治疗结果:腹痛完全消失333例,占67.1%;腹痛明显减 On December 6th, 1983, the new drug appraisal meeting for Tartary Buckwheat was held in Kunming City. The meeting was chaired by Yunnan Provincial Department of Health, Yunnan Pharmaceutical Corporation and Yunnan Provincial Science and Technology Commission. Swertia sclerophylla is a new antispasmodic and painkilling drug extracted from Swertia patens Burk. From 1981 to 1983, the extraction, isolation and structure identification of tartary buckwheat from the Yunnan Institute of Materia Medica was conducted. Pharmacology, Toxicology, Pilot Processes, Drug Quality Standards, etc. were studied. Jiangxi Medical College conducted a pharmacokinetic study of ~3H - Swertia sclerophylla, and the Yunnan Provincial Institute of Drug Control coordinated the quality of the drug. In the standard study, Chuxiong Prefecture Institute of Drug Control collaborated on some chemical research work, and 496 clinical efficacy observations were performed by 9 clinical collaboration hospitals including Kunming Children’s Hospital and the First Affiliated Hospital of Kunming Medical College. The participants passed the technical appraisal unanimously and concluded that swertia sclerophylla has better smooth muscle spasm and certain analgesic and sedative effects. After 496 cases of clinical observation, the effect was satisfactory. In 496 cases, there were 82 cases of gastrointestinal fistula, 80 cases were effective, 2 cases were ineffective, and the effective rate was 97.5%; 128 cases of intestinal tsutsugamushi pain, 119 cases effective, 9 cases ineffective, 93% effective; 128 cases of gastroenteritis pain 112 cases were effective, 16 cases were invalid, the effective rate was 87.5%; 64 cases of biliary ascariasis and other biliary tract disease pain, 51 cases effective, 13 cases ineffective, the effective rate was 79.7%; 94 cases of abdominal pain caused by other diseases, effective 76 Cases, invalid 18 cases, the effective rate was 80.8%. In 496 cases, the following treatment results were obtained: abdominal pain disappeared completely in 333 cases, accounting for 67.1%; abdominal pain was significantly reduced