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在大鼠下丘脑外侧区(LHA)微量注入五肽胃泌素(G-5)0.01/μg和0.05μg可明显增强胃窦的运动。达一反应可被切断迷走神经所阻断。提示在LHA存在的胃泌素可参与胃运动的调节,并可能通过迷走神经起作用。用免疫组化PAP方法可显示出LHA有含阳性颗粒的大型胃泌素免疫反应性细胞和神经纤维网,这些胃泌素免疫反应性细胞和神经纤维网,这些胃泌素神经细胞可能在调节胃运动功能中起重要作用。
Microinjection of pentagastrin (G-5) 0.01 / μg and 0.05 μg into the lateral hypothalamic area of rat (LHA) markedly enhances the movement of the antrum. One response can be blocked by vagotomy. Suggesting that the presence of gastrin in LHA may be involved in the regulation of gastric motility and may play a role through the vagus nerve. Using the immunohistochemical PAP method, it is possible to show that LHA has large gastrin-immunoreactive cells and nerve fiber webs containing positive particles, which are likely to be regulated by gastrin-type immunoreactive cells and nerve fiber network Stomach motor function plays an important role.