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目的 :研究亚临床甲状腺功能减退症与糖尿病肾脏疾病的相关性。方法 :选择2014年5月-2015年5月来我院就诊的合并DKD的II型糖尿病患者66例为实验对象,另取两组同数量的SCH合并II型糖尿病者与单纯糖尿病组为对照对象,分别为单纯组66例与SHC组66例。为其进行常规,生化检查。结果:和单纯组相比,合并SHC组的肌酐指数明显较高,组间数据存在统计学意义,BUN指数较高,组间数据存在统计学意义,P<0.05.肾小球过滤率明显偏低,组间数据存在统计学意义。两组相比较可知,SHC组的肾功能不全比例明显比单纯组高,P<0.05.将肾小球过滤率视为因变量,实施多因素分析,结果证明,SCH为DKD的独立危险因素。结论 :DKD合并SCH者发生肾功能损害的概率比单纯糖尿病组患者概率大,其发生肾功能不全概率较高,SCH可能为DKD患者肾功能不全的因素。
Objective: To study the relationship between subclinical hypothyroidism and diabetic nephropathy. METHODS: Sixty-six patients with type 2 diabetes mellitus with DKD treated in our hospital from May 2014 to May 2015 were selected as experimental subjects. Two groups of patients with type II diabetes mellitus complicated with type II diabetes and simple diabetes mellitus , Respectively 66 cases in simple group and 66 cases in SHC group. For its routine, biochemical tests. Results: Compared with the simple group, creatinine index in the SHC group was significantly higher, the data between the groups was statistically significant, the BUN index was higher, the data between the groups had statistical significance, P <0.05, glomerular filtration rate was significantly Low, there was statistical significance between groups. Compared with the two groups, SHC group was significantly higher than the simple group of renal insufficiency, P <0.05. The glomerular filtration rate as a dependent variable, the implementation of multivariate analysis, the results show that SCH is an independent risk factor for DKD. Conclusion: The probability of renal dysfunction in patients with DKD combined with SCH is higher than that in patients with simple diabetes mellitus, and the probability of renal dysfunction is high. SCH may be the cause of renal dysfunction in DKD patients.