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胃食管反流(GER)与牛奶蛋白过敏(CMA)都是婴儿期常见的疾病。近年来,关于两者之间关系的研究逐渐增多,有报道认为1岁以内婴儿的 GER,约50%可能与 CMA 有关,因此全面认识 CMA 在婴儿 GER 发生和发展中的作用,对于提高临床诊疗水平具有重要意义。该综述试图阐述婴儿 CMA 与 GER 相关的研究进展,包括流行病学、发病机制、临床表现、诊断和治疗。“,”Gastroesophageal reflux (GER) and cow’s milk allergy (CMA) are common disorders in infants. In recent years, more and more research has investigated the relationship between these two diseases. Some studies reported that about half of the cases of GER in infants younger than 1 year may be an association with CMA. Therefore, overall understanding the role of CMA on the pathogenesis of GER has a great importance on improving clinical level of diagnosis and therapy. This review article tried to elaborate advances in research on the relationship between CMA and GER in infants, including epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment.