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作者回顾性调查了NMH和VALMC两所医院实验室自1980年3月～1982年10月期间所有检测乙型肝炎标志物的患者,总HBsAg和抗-HBs检出率VALMC(39.4%)较NMH(14.5%)显著为高,但血清中同时出现HBsAg和抗-HBs的检出率却相近似(0.9%和0.5%)。在同时检出HBs-Ag/抗-HBs的64例中,36例经长期(6～57个月)随访,并以33例HBsAg阳性/抗-HBs阴性患者按年龄、性别和种族相配作对照,结合临床和病理资料进行了分析。结果表明,试验组和对照组肝脏疾病的严重程度相仿。病理证实的慢性迁延性肝炎(CPH)分别为2和4例;慢性活动性肝炎(CAH)为4和3例;肝硬变为2和3例。
The authors retrospectively examined all patients tested for hepatitis B markers from March 1980 to October 1982 in two hospital laboratories in NMH and VALMC. The detection rate of total HBsAg and anti-HBs, VALMC (39.4%), was higher than that of NMH (14.5%) was significantly higher but the detection rates of concurrent HBsAg and anti-HBs in serum were similar (0.9% and 0.5%). Among the 64 cases with simultaneous detection of HBs-Ag / anti-HBs, 36 cases were followed up for a long time (6-57 months), and 33 cases of HBsAg-positive / anti-HBs-negative patients were matched by age, sex and race , Combined with clinical and pathological data were analyzed. The results showed that the severity of liver disease in the experimental and control groups was similar. Pathologically confirmed chronic persistent hepatitis (CPH) were 2 and 4, respectively; chronic active hepatitis (CAH) was 4 and 3; cirrhosis was 2 and 3.