论文部分内容阅读
目的 探讨咳嗽变异型哮喘 (CVA)与慢性咳嗽病因的相关性。方法 对原因不明的慢性咳嗽患者作肺通气功能检查 ,FEV1实测值 /预计值 <80 %者行支气管舒张试验 ,FEV1实测值 /预计值≥ 80 %予气道反应性测定 ,并对咳嗽变异型哮喘与慢性咳嗽的病因进行相关性研究。结果 172例肺通气功能检查 ,FEV1实测值 /预计值 <80 %者 118例 ,支气管舒张试验阳性 37例、阴性 81例 ;FEV1实测值 /预计值≥ 80 %者 5 4例 ,接受磷酸组织胺药物吸入支气管激发试验 ,气道反应性增高者 15例 ,气道反应性正常者 39例 ;据此 ,本组病人可诊断咳嗽变异型哮喘 5 2例 ,占慢性咳嗽病因的 30 .2 % ,由此可见咳嗽变异型哮喘是慢性咳嗽的重要病因 ,咳嗽变异型哮喘与慢性咳嗽的病因密切相关。结论 咳嗽变异型哮喘是慢性咳嗽的主要病因 ,两者密切相关 ,咳嗽变异型哮喘是哮喘的前驱状态 ,可发展为典型的哮喘 ,对病因为咳嗽变异型哮喘的慢性咳嗽患者早期发现并施以正确的治疗 ,可以预防典型哮喘的发病。
Objective To investigate the correlation between cough variant asthma (CVA) and the cause of chronic cough. Methods Pulmonary ventilation tests were performed on patients with chronic cough of unknown origin. The FEV1 measured value / predicted value <80% was measured by bronchodilator test, the measured value of FEV1 / predicted value ≥ 80%, and the cough variability The relationship between asthma and chronic cough was studied. Results A total of 172 patients with pulmonary function tests were enrolled in the study. FEV1 measured value / predicted value <80% were 118, bronchodilator test positive 37, and negative 81; FEV1 measured / expected 80% Drug inhalation bronchial provocation test, 15 cases of increased airway reactivity, 39 cases of normal airway responsiveness; accordingly, this group of patients can be diagnosed cough variant asthma in 52 cases, accounting for 30.2% of the cause of chronic cough, This shows that cough variant asthma is an important cause of chronic cough, cough variant asthma and the cause of chronic cough are closely related. Conclusions Cough variant asthma is the main cause of chronic cough. The two are closely related to each other. Cough variant asthma is a precursor of asthma and can develop into typical asthma. Patients with chronic cough due to cough variant asthma were detected early and applied Correct treatment can prevent the onset of typical asthma.