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有机锗倍半硫化物的合成是有机锗抗癌药物研究中的热点之一。在路易斯碱(如吡啶或三乙胺)存在下,经有机锗三氯化物溶液中通干燥的硫化氢气体制得有机锗倍半硫化物的方法有许多缺点,如无法计算吸收的硫化氢的量、设备复杂、操作困难并产生硫化氢臭味和毒性。我们用无水硫化钠直接与有机锗三氯化物作用即可得到有机锗倍半硫化物。利用此法合成了8种有机锗倍半硫化物:
The synthesis of organogermanium sesquisulfides is one of the hot topics in the study of organic germanium anticancer drugs. There are many disadvantages to making organogermanium sesquisulfides in the presence of Lewis bases (such as pyridine or triethylamine) by passing dry hydrogen sulphide gas in an organogerman trichloride solution, such as the inability to calculate the amount of absorbed hydrogen sulphide , Complex equipment, difficult operation and hydrogen sulfide odor and toxicity. We use anhydrous sodium sulfide directly with organic germanium trichloride role can be obtained organic germanium sesquisulfide. Eight organic germanium sesquisites were synthesized by this method: