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目的 :探讨不稳定型心绞痛 (UAP)病人的血清肌钙蛋白I(cTnI)水平与心绞痛分级 ,短期心脏事件发生率的关系。方法 :6 4例UAP患者 ,30例健康对照组进行了血清cTnI测定 ,并观察了 30d的心脏事件发生率。结果 :UAP组血清cTnI值明显高于健康对照值 (P <0 0 1) ,UAP组内随着Braunwald临床分级增高 ,血清cTnI值亦相应增高 (P <0 0 5 ) ,同时UAP组内cTnI阳性组 (≥ 0 0 4ng/ml)短期心脏事件发生率明显高于cTnI阴性组 (<0 0 4ng/ml) (P <0 0 1)。 结论 :血清cTnI与UAP的严重程度相关 ,并对短期心脏事件的预测有着重要的临床意义。
Objective: To investigate the relationship between the level of cTnI and the grade of angina pectoris and the incidence of short-term cardiac events in patients with unstable angina pectoris (UAP). Methods: Serum cTnI levels were measured in 64 UAP patients and 30 healthy controls, and the incidence of cardiac events was observed 30 days later. Results: Serum cTnI level in UAP group was significantly higher than that in healthy control group (P <0.01). The level of cTnI in UAP group increased with Braunwald clinical grade (P <0 05) The incidence of short-term cardiac events in the positive group (≥ 0 04ng / ml) was significantly higher than that in the cTnI-negative group (<0 04ng / ml) (P <0.01). Conclusion: Serum cTnI is related to the severity of UAP and has important clinical significance for the prediction of short-term cardiac events.