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用~H-Lcu参入的方法,观察到小鼠腹水型Tu—RNA能显著地抑制小鼠脾淋巴细胞的蛋白质合成。这种抑制效应无RNA来源的肿瘤特异性,但具有组织特异性。主要活性成分可能存在于RNasc酶解混合物的Scphadex G—100层析第二组分中。
With the method of ~H-Lcu incorporation, it was observed that mouse ascites Tu-RNA could significantly inhibit protein synthesis of mouse spleen lymphocytes. This inhibitory effect has no RNA-derived tumor specificity but is tissue-specific. The main active ingredient may be present in the second fraction of the Scphadex G-100 chromatographic fraction of the RNasc enzymatic digest mixture.