１９９１年５～１０月，作者从肠道门诊痢疾患者的粪便中分离出３２５株志贺氏菌，对其中的２４８株做１７种抗菌药物的敏感试验，对其结果进行分析。同时做了大肠埃希氏菌与志贺氏菌的耐药质粒接合传递试验，并对志贺氏菌耐药性原因进行了初步探讨。 From May to October 1991, 325 shigella isolates were isolated from the stool of patients with gut dysentery in the gut outpatient department, and 248 of them were tested for susceptibility to 17 antibiotics. Results were analyzed. At the same time, E. coli and Shigella resistant plasmid conjugation experiments were carried out, and the causes of Shigella resistance were discussed.