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解决不孕不育是医学研究的一大难题,有趣的是,从发病比例而言男性和女性也基本平等,大致上各占一半[1]。男性不育主要表现为无精、少精。影响男性不育的因素有很多,其中Y染色体的异常包括染色体的数目、大小异常,倒位及微缺失等[2]。Y染色体微缺失现在被认为是男性特发性不育中一种重要的遗传学病因。
To solve infertility is a major problem in medical research. What is interesting is that both men and women are basically equal in terms of incidence, and roughly half in each. [1] Male infertility is mainly manifested as infertility, less refined. There are many factors affecting male infertility, including Y chromosome abnormalities, including the number of chromosomes, size abnormalities, inversion and microdeletions [2]. Y chromosome microdeletion is now considered as an important genetic cause of idiopathic male infertility.