近年来常论及重症肌无力的自身免疫病因学说,关于ACTH、类固醇激素等免疫抑制剂的治疗报告也多次出现。本文对15例用抗胆硷酯酶剂无效的小儿重症肌无力患者使用环磷铣胺治疗,剂量2毫克/公斤,分为每日两次,较长期使用;作为对照组,观察13例单用抗胆硷酯酶剂有效的病例。两组均先用抗胆硷酯酶剂吡啶斯的明,酶抑宁(阿伯农),且尽早以最适当剂量作正规治疗。环磷酰胺组治疗结果 In recent years, often talking about the theory of autoimmune myasthenia gravis theory, on the ACTH, steroid hormones and other immunosuppressive treatment reports also appeared many times. In this paper, 15 cases of patients with myasthenia gravis ineffective anticholinesterase use cyclophosphamide treatment, the dose of 2 mg / kg, divided into two times a day, more long-term use; as a control group, the observation of 13 cases Use anticholinergic agents effective cases. Both groups first with anti-cholinesterase pyridostigmine, enzyme inhibition Ning (Arboron), and as soon as possible with the most appropriate dose for formal treatment. Cyclophosphamide treatment results