目的比较参芪扶正注射液联合DA化疗方案或单纯DA方案治疗急性非淋巴细胞白血病(ANLL)的疗效及不良反应。方法入选的60例ANLL患者分为两组,观察组32例,采用参芪扶正注射液联合DA化疗方案治疗;对照组28例,单纯用DA方案治疗。观察两组缓解率、临床症状、不良反应等指标。结果观察组CR率为71.86%,明显高于对照组的53.57%(P<0.05);观察组总有效率(CR+PR)为93.72%明显高于对照组的71.43%(P<0.01)。两组临床症状改善率分别为75.00%和53.57%,两组比较有显著差异(P<0.05)。观察组神经毒性及心脏毒性的发生率明显低于对照组(P<0.01)。结论参芪扶正注射液联合DA化疗方案治疗急性非淋巴细胞白血病可起到减轻化疗的不良反应,提高治疗效果的作用。 Objective To compare the efficacy and side effects of Shenqi Fuzheng injection combined with DA chemotherapy or simple DA regimen in the treatment of acute non-lymphocytic leukemia (ANLL). Methods Sixty ANLL patients were divided into two groups. The observation group consisted of 32 cases. The Shenqi Fuzheng injection combined with DA chemotherapy was used. In the control group, 28 cases were treated with DA alone. The two groups were observed the remission rate, clinical symptoms, adverse reactions and other indicators. Results The CR rate in the observation group was 71.86%, which was significantly higher than that in the control group (53.57%, P <0.05). The total effective rate (CR + PR) in the observation group was 93.72%, significantly higher than that in the control group (71.43%, P <0.01). The clinical symptom improvement rates of the two groups were 75.00% and 53.57%, respectively, with significant difference between the two groups (P <0.05). The incidence of neurotoxicity and cardiotoxicity in observation group was significantly lower than that in control group (P <0.01). Conclusion Shenqi Fuzheng injection combined with DA chemotherapy in the treatment of acute non-lymphocytic leukemia can play a role in alleviating the adverse reactions of chemotherapy and improving the curative effect.