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妊娠相关乳腺癌是指在妊娠期、哺乳期以及分娩后1年内确诊的原发性乳腺癌,是一种特殊类型的乳腺癌。[1]本文就妊娠相关乳腺癌的特点[2]叙述如下。1妊娠相关乳腺癌的生物学特征妊娠期乳腺癌的雌激素受体(ER)阳性率仅占25%[3],而妊娠期间雌激素、孕激素明显增加,对此查阅相关资料,解释如下:由于妊娠期间血液中存在大量的雌激素,使得血液中雌激素受体达到饱和,也使得肿瘤组织的雌激素及孕激素受体下调。妊娠期乳腺癌的另外一个生物学特性是p53和Ki-67的表达率较
Pregnancy-related breast cancer is a specific type of breast cancer that is diagnosed during pregnancy, lactation and within 1 year of childbirth. [1] This article describes the features of pregnancy-related breast cancer [2] as follows. 1 biological characteristics of pregnancy-related breast cancer Pregnancy breast cancer estrogen receptor (ER) -positive rate of only 25% [3], and estrogen and progesterone during pregnancy significantly increased, access to relevant information on this, explained as follows : Due to the large amount of estrogen present in the blood during pregnancy, the estrogen receptor in the blood is saturated and the estrogen and progestin receptors in the tumor are down-regulated. Another biological characteristic of gestational breast cancer is the expression rate of p53 and Ki-67