论文部分内容阅读
过去对于慢性活动性肝炎病人的预后及治疗只能根据肝脏活检所见肝脏损害严重程度来决定。作者发现氨基比林呼吸试验与肝组织学检查所见肝损伤严重程度一致,其机理在于氨基比林呼吸试验(简称ABT)能反映肝微粒体功能和存活的肝细胞数量,从而能反映肝损伤的严重程度。ABT试验步骤如下:2mg/kg~(13)C-氨基比林溶于50ml水后口服,收集呼吸标本,根据~(13)C计算出呼出的CO_2,从而判断出~(13)C-氨基比林在肝微粒体中的代谢率。作者测定了55例组织学证实的慢性迁延性肝炎(下称慢迁肝)、慢性活动性肝炎(下称慢活肝)、慢性活动性肝炎伴有桥状
In the past, the prognosis and treatment of patients with chronic active hepatitis can only be determined by the severity of liver damage seen in liver biopsy. The authors found that the severity of liver damage seen in aminopyrine breath tests and liver histology was consistent with the mechanism that the aminopyrine breath test (ABT) reflects the number of liver microsomes and the number of surviving hepatocytes and thus reflects liver damage The severity of ABT test procedure is as follows: 2mg / kg ~ (13) C-aminopyrine dissolved in 50ml water after oral administration, collecting respiratory samples, calculated according to ~ (13) C exhaled CO_2 to determine ~ Billing’s metabolic rate in liver microsomes. The authors examined 55 cases of histologically confirmed chronic persistent hepatitis (hereinafter referred to as slowly moving liver), chronic active hepatitis (hereinafter referred to as slow living liver), chronic active hepatitis accompanied by bridge