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２２例急性白血病和４例恶性淋巴瘤患儿于强化化学疗法（强化疗）后，应用粒细胞－巨噬细胞集落刺激因子（ＧＭ－ＣＳＦ）５－８μｇ／（ｋｇ·ｄ），ｓｃ，ｑｄ，连用２－１０ｄ，作为支持疗法，以缩短其骨髓抑制期。临床统计资料结果显示，应用ＧＭ－ＣＳＦ治疗组患儿．其强化疗后平均骨髓抑制期为１２．１±ｓ２．９ｄ，平均发热时间为５．３±２．３ｄ，均明显低于对照组平均骨髓抑制期１９±４ｄ和发热时间７．６±２．４ｄ，Ｐ＜０．０５。应用ＧＭ－ＣＳＦ后未见明显不良反应。
22 cases of acute leukemia and 4 cases of malignant lymphoma after intensive chemotherapy (intensive chemotherapy), the application of granulocyte-macrophage colony stimulating factor (GM-CSF) 5-8μg / (kg · d), sc, qd , Combined with 2-10d, as a supportive therapy to shorten its bone marrow suppression period. Clinical statistics results show that the application of GM-CSF treatment group of children. The average duration of myelosuppression after intensive chemotherapy was 12.1 ± s2.9d and the average fever time was 5.3 ± 2.3d, which were significantly lower than the mean myelosuppression period of 19 ± 4d and the fever time of 7.6 ± 2 .4d, P <0.05. There was no obvious adverse reaction after applying GM-CSF.