论文部分内容阅读
目的:观察传统古方痛风灵的抗炎、镇痛、抗痛风等作用。方法:采用了炎症、疼痛及痛风模型进行药效学研究。结果:痛风灵对二甲苯所致小鼠耳肿胀、蛋清及角叉菜胶所致小鼠足肿胀均有明显抑制作用;痛风灵能明显对抗尿酸钠所致大鼠痛风性关节炎,对醋酸所致小鼠扭体反应及热板引起小鼠足痛有对抗作用。结论:痛风灵具有明显的抗炎作用、镇痛作用和抗痛风作用。
Objective: To observe the anti-inflammatory, analgesic, and anti-gout effects of traditional ancient Fangfengfengling. Methods: Pharmacodynamic studies using inflammation, pain, and gout models were performed. RESULTS: Tongfengling significantly inhibited mouse ear swelling, egg white and carrageenan-induced foot swelling in xylene-induced mice; Tongfengling significantly against uric acid-induced gouty arthritis in rats. The mice’s writhing response and hot plate caused the mice to have an antagonistic effect on foot pain. Conclusion: Gout has a significant anti-inflammatory, analgesic and anti-gout effects.