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目的探讨急性加重期及稳定期慢性阻塞性肺疾病(COPD)患者情绪状态与患者BODE指数的联系。方法 COPD患者85例分为急性加重期(AECOPD组,48例)和稳定期(SCOPD组,37例),采用Hamilton焦虑量表(HAMA)和Hamilton抑郁(HAMD)评分评估患者焦虑和抑郁情况,BODE指数预测COPD患者病情及预后。分析COPD患者情绪状态与患者BODE指数的相关性。结果两组患者HAMA评分均大于7分,HAMD评分均大于8分。两组患者BODE指数、HAMA评分、HAMD评分及动脉血氧分压均有统计学差异(P<0.05)。HAMA和HAMD评分与BODE指数呈线性关系(R2=0.575和R2=0.503)。结论通过临床易于操作的量表分析COPD患者情绪状态变化特点,便于临床医师尽早认识并处理患者的异常情绪状态。
Objective To investigate the relationship between emotional status and BODE in patients with acute exacerbation and stable chronic obstructive pulmonary disease (COPD). Methods 85 patients with COPD were divided into acute exacerbation (AECOPD, n = 48) and stable (SCOPD, n = 37). HAMA and Hamilton Depression (HAMD) scores were used to evaluate anxiety and depression, BODE index predicts disease and prognosis in COPD patients. Analysis of COPD patients emotional state and patient BODE index correlation. Results HAMA scores of both groups were greater than 7 points, HAMD scores were greater than 8 points. BODE index, HAMA score, HAMD score and partial pressure of arterial oxygen in both groups were significantly different (P <0.05). The HAMA and HAMD scores were linear with the BODE index (R2 = 0.575 and R2 = 0.503). Conclusions The characteristics of emotional state changes in patients with COPD are analyzed by a clinically easy-to-operate scale, so that clinicians can recognize and handle abnormal emotion state as soon as possible.