Histone deacetylase inhibitor suberoylanilide hydroxamic acid alleviates liver fibrosis by suppressi

来源 :国际肝胆胰疾病杂志：英文版 | 被引量 : 0次 | 上传用户：xw54073601

【摘要】

：

Background:Histone deacetylases(HDACs)inhibitors are new anti-fibrotic drugs that inhibit the activity of hepatic stellate cells.The present study focused on th

【作者】

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Yao Wang Lei Zhao Fang-Zhou Ji

【机构】

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DepartmentofInfectiousDiseases,DepartmentofInfectiousDiseases

【出处】

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国际肝胆胰疾病杂志：英文版

【发表日期】

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2018年5期

【关键词】

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ACETYLATION TRANSFORMING growth factor-β1 Liver FIBROSIS Suberoylanilide hydroxa

【基金项目】

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This study was supported by a grant from the National Natural Science Foundation of China(81870413).

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Background:Histone deacetylases(HDACs)inhibitors are new anti-fibrotic drugs that inhibit the activity of hepatic stellate cells.The present study focused on the anti-fibrotic function of HDAC inhibitor suberoylanilide hydroxamic acid(SAHA)by suppressing

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