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采用MTT法检测MNNG加热损伤诱发的胃粘膜异型增生大鼠脾脏NK细胞活性和淋巴细胞转化率，结果发现较正常对照组大鼠明显降低，表明胃癌前病变大鼠存在着免疫功能的低下；运用中药胄尔康进行预防性治疗，则能明显提高胃粘膜异型增生大鼠的NK细胞活性，促进淋巴细胞的转化，且随剂量的增大而增强；同时，胃尔康还能减轻环磷酸胺引起的小鼠胸腺、脾脏的萎缩，并可防止环磷酰胺引起的小鼠外周血白细胞、淋巴细胞的减少。研究提示，胃尔康有调节机体免疫功能的作用，通过增强机体的免疫能力，从而有效地防治胃癌前病变的发生发展。
MTT assay was used to detect NK cell activity and lymphocyte transformation rate in spleen of gastric dysplasia rats induced by MNNG heat injury. The results showed that compared with the normal control rats, the NK cell activity was significantly reduced, indicating that the precancerous rats have low immune function; The traditional Chinese medicine Jerkang’s preventive treatment can significantly increase the activity of NK cells in gastric dysplasia rats, promote the transformation of lymphocytes, and increase with the increase of the dose; at the same time, Weierkang can also reduce the cyclophosphamide Atrophy of the thymus and spleen of mice was induced, and the reduction of white blood cells and lymphocytes in peripheral blood of mice induced by cyclophosphamide was prevented. Studies have shown that Gascon has the function of regulating the immune function of the body, and by strengthening the body’s immunity, it can effectively prevent the development of precancerous lesions.