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报道经病理确诊的乳腺癌、鼻咽癌、肺癌等51例骨转移患者行 ̄(153)Sm-EDTMP内照射重复治疗的疗效。结果骨痛消失、减轻和无效分别为17.6%、74.5%和7.8%,总有效率为92.1%。对15例治疗前后全身骨显像作对比观察,其中7例病灶稳定,其余8例有19个病灶消失或部分消失,同时2例出现新的骨转移灶。个别病例CT动态观察受累骨可见骨质修复,大多数患者全身状况改善,一过性白细胞降低、恶心仅占3.9%,无其他毒副作用。对 ̄(153)Sm-EDTMP治疗骨转移癌过程中可能的影响因素作了分析。
Reported the pathological diagnosis of breast cancer, nasopharyngeal carcinoma, lung cancer in 51 cases of bone metastases in patients with ~ (153) Sm-EDTMP treatment of repeated treatment. Results The disappearance, alleviation and ineffectiveness of bone pain were 17.6%, 74.5% and 7.8% respectively, with a total effective rate of 92.1%. Fifteen cases were compared before and after treatment of bone imaging, of which 7 cases stable, the remaining 8 cases of 19 lesions disappeared or partially disappeared, while 2 cases of new bone metastases. Some cases of CT dynamic observation of bone involvement can be seen bone repair, the majority of patients with improved general condition, transient white blood cells decreased nausea only accounted for 3.9%, no other side effects. The possible influencing factors of ~ (153) Sm-EDTMP in the treatment of bone metastases were analyzed.