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目的：探讨哮喘息儿外周血分化群（CD）56、CD25水平检测的临床意义。方法：应用流式细胞仪（FCM）检测哮喘患儿外周血单个核细胞中CD56+、CD25+细胞数。结果：缓解期组CD56十细胞数百分比[（12.0±3．1）％］及CD25+细胞数百分比[（4．1±2．2）％]与正常对照组比较均无显著性差异（P＞0．05）；哮喘发作组CD56+细胞数百分比[（9、4±2．2）％]低于正常对照组[（11．9±3．2）％]及缓解期组（P＜0．01）；哮喘发作组CD25+细胞数百分比[（7.2±2．1）％]高于正常对照组[（4．1±1．8）％]及缓解期组（P＜0．01）。结论：CD56+、CD25+细胞数与小儿哮喘的发病过程有一定关系。
Objective: To investigate the clinical significance of detection of CD56 and CD25 levels in peripheral blood of asthmatic children. Methods: The number of CD56 + and CD25 + cells in peripheral blood mononuclear cells of children with asthma was detected by flow cytometry (FCM). Results: The percentages of CD56 ten cells [(12.0 ± 3.1)%] and CD25 + cells [(4.1 ± 2.2)%] in remission group were not significantly different from those in normal control group (P> 0.05). The percentage of CD56 + cells in asthma attack group (9.4 ± 2.2%) was lower than that in normal control group (11.9 ± 3.2%) and remission group (P <0.05). 01). The percentage of CD25 + cells in asthma attack group was (7.2 ± 2.1)% higher than that in normal control group (4.1 ± 1.8%) and remission group (P0.01). Conclusion: The number of CD56 + and CD25 + cells is related to the pathogenesis of asthma in children.