地中海贫血是一种遗传性血红蛋白病,由珠蛋白基因的缺失或结构改变所引起.东南亚地区常有报导,大部分患者为华侨,我国多发生在广东、广西、四川等省、区.在我国14省、区的脐血检查中α-地中海贫血发生率为2.93%,而广西高达14.9%,占高发区首位.根据我院产科统计,1971～1980年院内分娩新生儿畸形中,胎儿水肿22例,占畸形的31.4%.本病引起的胎儿水肿一般在妊 Thalassemia is a hereditary hemoglobinopathy caused by a deletion or structural alteration of the globin gene, which is often reported in Southeast Asia, most of whom are overseas Chinese, most of which occur in provinces and regions such as Guangdong, Guangxi, Sichuan, etc. In our country 14 province, district umbilical cord blood examination in the incidence of α-thalassemia 2.93%, while Guangxi as high as 14.9%, accounting for the first high incidence.According to our hospital obstetric statistics, 1971 ~ 1980 hospital birth neonatal malformation, fetal edema 22 Cases, accounting for 31.4% of deformities. The disease caused by fetal edema generally in pregnancy