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治疗单纯性肾病少尿、浮肿及低蛋白血症时,常用白蛋白,但实际效果却不尽人意:患者尿量无明显增多,复查血浆蛋白却比输入白蛋白前还低。为探讨这一问题,进行了初步对照观察。 临床资料 (1)对象:初发单纯性肾病20例,均符合1979年全国小儿肾脏病科研协作组制定的诊治标准。随机分成2组,甲组10例,男7例,女3例,平均年龄7±3.5岁;乙组10例,男6例,女4例,平均年龄6±4岁。(2)治疗方法:两组均予常规利尿、强的松等治疗,甲组在少尿浮肿期连续或隔日输入白蛋白10g/次,共2～5次。(3)观察方法:全部病例入院时均查血浆蛋白、BUN等,在输完全部白蛋白的同样时间,复查血浆蛋白。(4)治疗前、后血浆蛋白检测结果见表。
Treatment of simple nephropathy oliguria, edema and hypoalbuminemia, albumin, but the actual effect is not satisfactory: no significant increase in urine output, review of plasma protein than before the input albumin is also low. To explore this issue, conducted a preliminary control observation. Clinical data (1) Subjects: initial simple nephropathy in 20 cases, are in line with the 1979 national pediatric nephropathy research collaboration group developed criteria for diagnosis and treatment. A group of 10 patients, 7 males and 3 females, mean age 7 ± 3.5 years old; B group of 10 patients, 6 males and 4 females, the average age of 6 ± 4 years. (2) Treatment: Both groups were given routine diuretic and prednisone treatment. Group A received albumin 10g / time for 2 or 5 times continuously or every other day in oliguric edema. (3) observation method: All cases were admitted to the hospital check plasma protein, BUN, lose all albumin in the same time, review the plasma protein. (4) before and after treatment plasma protein test results shown in the table.