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对肿瘤引起疼痛的发生率和严重程度的估计尚缺乏大宗的流行病学研究,但多数报告表明,中等程度到严重疼痛占主动接受治疗肿瘤病人的1/3,占进展期病人的60～90%。
Estimates of the incidence and severity of tumor-induced pain are still lacking in major epidemiological studies, but most reports indicate that moderate to severe pain account for 1/3 of active tumor patients and 60 to 90 of advanced patients. %.