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创伤或烧伤后机体处于超高代谢,大量蛋白质分解,常表现有严重的负氮平衡,血清蛋白质和氨基酸明显下降。70年代静脉高营养的技术发展以后,得以从静脉途径补充足量的氨基酸和热量,解决病人单纯依靠摄食不能满足增长的营养需要。我们在研制成功通用型的11种结晶氨基酸注射液之后。根据创伤的代谢特点,又研制了17种结晶氨基酸注射液,通过中试生产和临床应用,已由北京制药厂生产。动物试验和临床观察的结果表明烧伤后血中游离氨基酸大多下降,尤其是许多非必需氨基酸的变化甚至比必需氨基酸还明显。如苏、丝、色、组、甘、谷、丙、脯氨酸是烧伤后容
After the trauma or burn, the body is in high metabolism, a large number of protein decomposition, often showed a serious negative nitrogen balance, serum protein and amino acids decreased significantly. 70 years after the development of intravenous nutrition technology to be able to supplement enough amino acids and calories from the venous route to address the patient simply rely on feeding can not meet the nutritional needs of growth. We have successfully developed a common type of 11 kinds of crystalline amino acid injection. According to the metabolic characteristics of trauma, but also developed a 17 kinds of crystalline amino acid injection, through pilot production and clinical application, has been produced by the Beijing Pharmaceutical Factory. The results of animal experiments and clinical observations showed that most of the free amino acids in the blood after burn were decreased, especially the changes of many non-essential amino acids were even more obvious than the essential amino acids. Such as the Soviet Union, silk, color, group, Gan, Valley, C, proline is burned content