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雷公藤具有雄性抗生育作用早已被证实,且不影响性功能,可复性好.但是若要开发雷公藤成为一个男性避孕中药,在有效抗生育作用剂量下对机体免疫功能的影响必须研究清楚.鉴于雷公藤是一种治疗自身免疫病的药物,人们已公认其在自身免疫病治疗剂量下对机体免疫功能有抑制作用.我们以往的实验工作已证实雷公藤有效抗生育阈剂量低于自身免疫治疗用量.而且有文献报道雷公藤在有效抗生育阈剂量下对机体体液免疫功能无明显影响,抗生育剂量比体液免疫抑制剂量低.本文对不同剂量雷公藤糖浆对生殖功能和免疫功能的影响进行了研究,旨在探讨有效抗生育阈剂量雷公藤糖浆对免疫功能的影响.
Tripterygium with male antifertility has long been confirmed, and does not affect sexual function, can be retrofitted, but to develop Tripterygium as a male contraceptive Chinese medicine, the effective anti-fertility effects of dose on the body’s immune function must be studied clearly Given that Tripterygium is a drug for the treatment of autoimmune diseases, it has been recognized that it inhibits the immune function of the body at a therapeutic dose of autoimmune diseases, and our previous experimental work has demonstrated that the effective anti-fertility threshold dose of Tripterygium wilfordii is lower than itself Immunotherapy dose.And it has been reported in the literature that the effective anti-fertility threshold dose of triptolide had no significant effect on the humoral immune function of the body, anti-fertility dose lower than humoral immunosuppressive dose.This article different doses of Tripteryllium syrup on reproductive and immune function The impact was studied in order to investigate the effect of an effective anti-fertility threshold dose of Tripterygium wilfordii on immune function.