论文部分内容阅读
目的:观察肝肾综合征(HRS)、失代偿性肝硬化病人血浆白三烯C_4(LTC_4)的水平及其与肾功能损害的关系。方法:检测HRS、失代偿性肝硬化而肾功能正常患者和正常对照组的血浆LTC_4和肌酐浓度。结果:失代偿性肝硬化患者血浆LTC_4增高,合并HRS者增高更显著,HRS患者血浆LTC_4与肌酐浓度有显著相关性。结论:LTC_4在肝硬化并发HRS的过程中具有重要作用。
Objective: To observe the level of plasma leukotriene C_4 (LTC_4) in patients with hepatorenal syndrome (CHF) and decompensated cirrhosis and its relationship with renal dysfunction. Methods: Plasma concentrations of LTC_4 and creatinine were measured in patients with HRS, decompensated cirrhosis and normal renal function and normal controls. Results: Plasma LTC_4 increased in patients with decompensated cirrhosis and increased more significantly in patients with HRS. There was a significant correlation between plasma LTC_4 and creatinine in patients with HRS. Conclusion: LTC_4 plays an important role in the process of cirrhosis complicated with HRS.