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目的探索干预措施在妇科围手术期抗菌药物合理应用中的可行性,寻求适合我国国情的手术预防使用抗菌药物干预模式。方法随机抽取本院妇科2013年(干预前)妇科病历100例作为非干预组,2014年(干预后)妇科出院的手术病历100例作为干预组,比较两组的效果。结果干预组术后住院时间、总住院时间、术后感染率明显优于非干预组,差异有统计学意义(P<0.05)。干预组平均抗菌药物费用(174.85±54.32)元明显低于非干预组(304.15±81.82)元,差异有统计学意义(P<0.05)。结论采用的合理用药干预措施具有有效性和可行性,降低了医院单病种的药物治疗费用,缩短药物使用时间。
Objective To explore the feasibility of interventions in the rational application of perioperative antibacterials in gynecology and seek for the mode of intervention for the prevention of the use of antimicrobial agents in our country. Methods 100 gynecological cases of gynecology in our hospital in 2013 (before intervention) were selected as non-intervention group and 100 cases of gynecological operation after 2014 (intervention) as intervention group. The effects of two groups were compared. Results The postoperative hospital stay, total hospital stay and postoperative infection rate in the intervention group were significantly better than those in the non-intervention group (P <0.05). The average cost of antimicrobial drugs in intervention group (174.85 ± 54.32) yuan was significantly lower than that in non-intervention group (304.15 ± 81.82) yuan, the difference was statistically significant (P <0.05). Conclusions The reasonable medication interventions adopted are effective and feasible, reducing the cost of medical treatment for single-disease hospital and shortening the time of drug use.