患者男,51岁,因双足皮肤逐渐变黑于1986年4月8日入院。从入院前3年开始在冬季或遇冷后即感头晕、乏力、双足疼痛,劳动时心悸、气短,气温转暖时症状好转。患者曾于1983年12月10日收住院内科治疗。当时查体:重度贫血貌,皮肤巩膜轻度黄染,心肺正常,肝脾不大,足背动脉搏动有力。化验:血 Male, 51 years old, was admitted to hospital on April 8, 1986 due to darkening of the bipedal skin. From 3 years before admission in the winter or after the cold that feeling dizzy, fatigue, both feet pain, work-heart palpitations, shortness of breath, warm when the symptoms are getting better. The patient was admitted to the hospital on December 10, 1983 medical treatment. At that time physical examination: severe anemia appearance, skin scleral mild yellow dye, normal heart and lungs, liver and spleen, dorsalis pedis artery vigorous. Test: blood