本文报告50例新生儿患者在其疾病的不同时期血中C反应蛋白[CRP]和纤维连结蛋白[Fn]测定结果,新生儿感染性疾病40例,非感染性疾病10例,测定显示在新生儿感染性疾病的早期CRP即高于正常,Fn低于正常;于感染的极期,CRP水平显著增高,Fn明显降低;随着感染的控制;CRP趋于恢复,Fn也逐渐回升,认为CRP和Fn的联合测定及动态观察可作为新生儿感染早期诊断和疗效估计的重要指标之一。 This article reports the results of 50 cases of newborns in the blood of patients with different stages of the disease C-reactive protein [CRP] and fibronectin [Fn] measured results, 40 cases of neonatal infectious diseases, non-infectious diseases in 10 cases, Early infectious CRP is higher than normal, Fn is lower than normal; in the extreme period of infection, CRP levels were significantly increased, Fn was significantly reduced; with infection control; CRP tends to recover, Fn also gradually rose, that CRP And Fn combined determination and dynamic observation can be used as an important indicator of early diagnosis and treatment of neonatal infection.