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本文报告经额入路垂体腺瘤切除421例术后经再次手术及病理确诊复发23例,复发与年龄有关。肿瘤切除是否完整是复发的关键因素。肿瘤的侵袭性亦是术后复发的重要原因,本组肿瘤多属巨大型,病理发现有侵袭性,再次手术有恶化倾向,特别是向包膜及周围组织浸润,大体亦有侵袭性。本组1例Nelson氏综合征,提示复发的内分泌因素。再手术发现局部粘连,解剖关系严重紊乱;术后视觉障碍好转率明显下降;死亡率增加,认为再手术选择应慎重。
This article reports 421 patients who underwent trans-rejection pituitary adenoma reoperation and pathological diagnosis of recurrence in 23 cases, recurrence and age-related. The completeness of tumor resection is a key factor for recurrence. The invasiveness of tumors is also an important cause of postoperative recurrence. Most of the tumors in this group are of huge type. The pathology has been found to be invasive, and the reoperation has a tendency to worsen, especially to the infiltrating capsule and surrounding tissues, and it is generally invasive. This group of 1 case of Nelson’s syndrome, suggesting recurrence of endocrine factors. Local adhesions were found after reoperation, and the anatomical relationship was severely disordered; the improvement rate of visual impairment after surgery was significantly decreased; the mortality rate increased, and it was considered that reoperation should be carefully selected.