目的探讨经皮穿刺微波消融术治疗肝癌的临床疗效。方法选择近年来外科住院的28例原发性肝癌患者(28个结节)作为治疗对象,并随机选取同期普通部位原发性肝癌患者22例作为对照组,对照组患者给予经导管肝动脉栓塞化疗术,观察组在其基础上联合使用经皮穿刺微波消融术治疗,比较两组患者疗效。结果观察组较对照组中肿瘤完全坏死、肿瘤不完全坏死例数分别为22例、10例和6例、12例,观察组中3例患者出现发热、肝区疼痛、恶心,1年半后有27例存活,对照组有2例患者出现发热、恶心、呕吐,1年半后有16例存活,除并发症外,组间差异显著(P<0.05)。结论经皮穿刺微波消融术操作简单,创伤性小,准确率高,治疗肝癌的疗效可靠,为肝癌的治疗提供了新思路、新方法,帮助部分失去手术机会的患者延续生命,值得临床进一步研究和推广。 Objective To investigate the clinical efficacy of percutaneous puncture microwave ablation in the treatment of liver cancer. Methods Twenty-eight patients with primary liver cancer (28 nodules) who were hospitalized in recent years were enrolled in the study. Twenty-two patients with primary liver cancer at the same period were randomly selected as the control group. Patients in the control group were treated with transcatheter arterial embolization Chemotherapy, observation group on the basis of combined percutaneous microwave ablation, compared the efficacy of two groups of patients. Results The tumors in the observation group were completely necrotic compared with the control group. The number of cases with incomplete necrosis was 22, 10 and 6, respectively. In the observation group, 3 patients had fever, liver pain, nausea, There were 27 cases surviving, 2 cases in the control group had fever, nausea and vomiting, and 16 cases survived after 1 and a half years. There was significant difference between the two groups except complication (P <0.05). Conclusion Percutaneous microwave ablation is simple, less invasive and accurate. It has a reliable curative effect in the treatment of liver cancer and provides new ideas and new methods for the treatment of hepatocellular carcinoma. It is worth further clinical study to help patients with partial loss of surgical opportunity And promotion.