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在世界人口中,65岁以上老年人口占11％。由于老年人组织器官退化;肝肾功能减退;常有基础疾病或伴发恶性肿瘤发生;免疫功能降低;以及老年患者药代动力学的特点等;常在应用抗菌药物时,较青中年患者更易发生药物毒副或过敏反应。合理应用抗菌药物,使之既能有效及时控制感染,发挥治疗作用,又能尽量减少毒副反应和耐药性发生,防止不必要的滥用抗菌药物,这是极为重要的。合理应用抗菌药物需注意下列几点:
Among the world’s population, the elderly over the age of 65 account for 11%. Due to the aging of human organs and organs; liver and kidney dysfunction; often associated with underlying diseases or associated with malignant tumor; decreased immune function; and elderly patients pharmacokinetic characteristics; often in the use of antimicrobial agents, more young middle-aged patients More prone to drug side effects or allergic reactions. The rational use of antimicrobial drugs, so that it can effectively control infection in time, play a therapeutic role, but also minimize adverse reactions and drug resistance, to prevent unnecessary abuse of antimicrobial drugs, it is extremely important. Rational use of antimicrobial drugs need to pay attention to the following points: